Key result
Laparoscopic sleeve gastrectomy significantly improved left ventricular systolic and diastolic functions and reduced left ventricular mass (p<0.001) at 6 months, though galectin-3 levels did not significantly decrease.
Why the study?
The study was conducted to investigate the effect of laparoscopic sleeve gastrectomy on cardiac reverse remodeling and fibrosis in obese patients.
Does laparoscopic sleeve gastrectomy improve cardiac reverse remodeling and reduce serum Galectin-3 levels in morbidly obese patients?
Cohort (n=144)
No
Does laparoscopic sleeve gastrectomy improve cardiac reverse remodeling and reduce serum Galectin-3 levels in morbidly obese patients?
Laparoscopic sleeve gastrectomy in morbidly obese patients leads to significant weight loss and early reverse cardiac remodeling at 6 months, characterized by improved left ventricular mass and diastolic function.
Answers are grounded in this paper and cite their sources.
Should not yet change practice; hypothesis-generating for post-bariatric cardiac remodeling and leaves galectin-3 role unresolved.
No abstract yet. The journal hasn't published one we can show.
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Tepe et al. (2026) conducted a cohort in Morbid obesity (n=144). Laparoscopic sleeve gastrectomy vs. Healthy controls and preoperative baseline was evaluated on Left ventricular mass (g) (p=<0.001). Laparoscopic sleeve gastrectomy significantly improved left ventricular systolic and diastolic functions and reduced left ventricular mass (p<0.001) at 6 months, though galectin-3 levels did not significantly decrease.
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