Coronary Blood Flow in Women From the CENTURY Trial

JACC Imaging · cohort study. Coronary flow may need sex-specific norms: women's is 33% higher. Coronary Blood Flow in Women From the CENTURY Trial Clinically manifest CAD in women is delayed by up to 2 decades compared with men without a defined physiological basis. Are there sex differences in quantitative coronary blood flow and clinical outcomes among patients in the CENTURY trial? 1028 participants, Post hoc analysis of randomized CENTURY…. Female sex was associated with 33% higher rest and stress coronary blood flow and significantly lower rates of major adverse cardiac events compared with male sex (P<0.0001). Women had approximately half the rates of all-cause mortality (log-rank P = 0.0223), death or myocardial infarction (log-rank P = 0.0138), revascularization (log-rank P… Rest and stress coronary blood flow were 33% higher in women than in men across all comparable strata of age, body mass index, risk factors, and treatment. Read the evidence. See where experts stand. synapsesocial.com/papers/6aa7afef79e9260bc85aac80