Good coronary collateral circulation (Rentrop grade 3) was associated with significantly lower cTp-e intervals and cTp-e/QT ratios compared to poorer collateral grades in patients with stable coronary artery disease.
Cross-Sectional (n=203)
Single-blind
No
Does good coronary collateral circulation improve the Tp-e interval and Tp-e/QT ratio in patients with stable coronary artery disease?
Good coronary collateral circulation is associated with decreased dispersion of ventricular repolarization, which may contribute to a lower incidence of ventricular arrhythmias in patients with stable CAD.
Absolute Event Rate: 62.9% vs 70.4%
p-value: p=<0.001
BACKGROUND: The clinical utility of the Tp-e interval and Tp-e/QT ratio in the risk stratification of ventricular arrhythmic events is controversial. Therefore, we investigated the impact of CCC on these electrocardiographic indexes in the course of stable CAD. METHODS: Two hundred three consecutive patients with stable CAD who underwent coronary angiography and had documented total occlusion of one of the major coronary arteries were enrolled in this prospective cross-sectional study. The Tp-e interval and Tp-e/QT ratio were measured by 12-lead electrocardiogram. RESULTS: The Tp-e interval, cTp-e interval, Tp-e/QT ratio, and cTp-e/QT ratio were lower in the grade 3 CCC group compared with the others in all leads. Multivariate linear regression analyses was performed to identify the clinical factors affecting the cTp-e interval and was indicated that age (β = 0.261, P < 0.001), male sex (β = 0.334, P < 0.001), poor Rentrop grade (β = -0.228, P < 0.001), and NLR (β = 0.137, P = 0.027) were independent predictors of a prolonged cTp-e interval. CONCLUSION: It could be concluded that the decreased dispersion of ventricular repolarization might contribute to the lower incidence of ventricular arrhythmias and SCD in CAD patients with a good CCC.
Taşolar et al. (2014) conducted a cross-sectional in Stable Coronary Artery Disease (n=203). Coronary collateral circulation (Rentrop Grade 3) vs. Poor coronary collateral circulation (Rentrop Grade 0-2) was evaluated on cTp-e interval in lead V5 (ms) (p=<0.001). Good coronary collateral circulation (Rentrop grade 3) was associated with significantly lower cTp-e intervals and cTp-e/QT ratios compared to poorer collateral grades in patients with stable coronary artery disease.