Chronic Anticoagulant Therapy in Recurrent Embolism of Cardiac Origin

Article1 February 1953CHRONIC ANTICOAGULANT THERAPY IN RECURRENT EMBOLISM OF CARDIAC ORIGINSTUART W. COSGRIFF, M.D.STUART W. COSGRIFF, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-2-278 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMajor arterial occlusions by emboli constitute one of the serious complications encountered in patients with chronic cardiac disease, particularly in individuals with inactive rheumatic mitral stenosis. Clinically recognizable embolism occurs in from 4 to 8 per cent of patients with chronic rheumatic heart disease,1, 2 and 60 per cent of these experience multiple episodes of vascular occlusion. In individuals with multiple embolism 75 per cent of the recurrences take place within one year of the initial episode.3Mural thrombus formations in one or more chambers are found in between 13 and 56 per cent of the autopsy examinations of patients...Bibliography1. KohnLevine CMSA: An evaluation of the use of quinidine sulfate in persistent auricular fibrillation, Ann. Int. Med. 8: 923, 1935. LinkGoogle Scholar2. ParkinsonCampbell JM: Quinidine treatment of auricular fibrillation, Quart. J. Med. 22: 289, 1928. Google Scholar3. DaleyMattinglyHoltBlandWhite RTWCLEFPD: Systemic arterial embolism in rheumatic heart disease, Am. Heart J. 42: 566, 1951. CrossrefMedlineGoogle Scholar4. GraefBergerBuninde la Chapelle IARJJCE: Auricular thrombosis in rheumatic heart disease, Arch. Path. 24: 344, 1937. Google Scholar5. HarveyLevine EASA: A study of uninfected mural thrombi of the heart, Am. J. M. Sc. 180: 365, 1930. CrossrefGoogle Scholar6. Garvin CF: Mural thrombi in the heart, Am. Heart J. 21: 713, 1941. CrossrefGoogle Scholar7. HayLevine WESA: Age and auricular fibrillation as independent factors in auricular mural thrombi formations, Am. Heart J. 24: 1, 1942. CrossrefGoogle Scholar8. ShapiroSherwinRedishCampbell SSMHA: Prothrombin estimation: a procedure and clinical interpretation, Proc. Soc. Exper. Biol. and Med. 50: 85, 1942. CrossrefGoogle Scholar9. JordanScheifleyEdwards RACHJE: Mural thrombosis and arterial embolism in mitral stenosis. A clinicopathologic study of fifty-one cases, Circulation 3: 363, 1951. CrossrefMedlineGoogle Scholar10. LeonardCogan FCMA: Failure of ligation of the left auricular appendage in the prevention of recurrent embolism, New England J. Med. 246: 733, 1952. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented in part before a Clinical Session of the Graduate Fortnight of the New York Academy of Medicine on October 18, 1951. Received for publication July 2, 1952.From the Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital in the City of New York. 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Techniques and complicationsRecurrent myocardial infarction after cessation of anticoagulant therapyTherapie der HerzinsuffizienzPeripheral Arterial EmboliAnalysis of factors affecting the recurrence of thromboembolism off and on anticoagulant therapyStudies in Peripheral Arterial Occlusive DiseaseTHE SIGNIFICANCE OF HAEMORRHAGE DURING THE TREATMENT OF PATIENTS WITH THE COUMARIN ANTICOAGULANTSThe pathogenesis, prevention and medical management of peripheral arterial thrombosisProfound Bleeding after Dental Extractions during Dicumarol TherapyStudies on the anticoagulant phenindioneAnticoagulant therapy in coronary artery diseaseThe Treatment of Cerebrovascular AccidentThe present status of anticoagulantsZur Frage der Anticoagulantientherapie des HerzinfarktesZur Frage der Anticoagulantientherapie des Herzinfarktes 1 February 1953Volume 38, Issue 2Page: 278-287KeywordsAnticoagulant therapyAutopsyGraduate medical educationHeartHeart diseasesHospital medicineMitral stenosisSurgeonsThrombosis ePublished: 1 December 2008 Issue Published: 1 February 1953 PDF downloadLoading ...