Three-dimensional wall motion tracking revealed significant myocardial deformation impairments across different left ventricular adaptative responses to hypertension compared to normal geometry (P<0.05).
Observational (n=66)
Does 3D-wall motion tracking identify differences in myocardial deformation among hypertensive patients with different left ventricular adaptative responses?
3D-wall motion tracking can detect early and subtle myocardial deformation impairments in hypertensive patients with different left ventricular geometric adaptations.
p-value: p=<0.05
BACKGROUND: High blood pressure increases left ventricular (LV) after-load. Furthermore, LV response to that high blood pressure varies among different subjects. Nevertheless, myocardial deformation behavior in these different adaptative responses has not been analyzed until now. METHODS: Prospective study in which 66 consecutive hypertensive patients were enrolled in between May and August 2009. Every patient underwent a standard echocardiographic study and a three-dimensional-wall motion tracking (3D-WMT) study. The patients were classified according to parameters derived from echocardiography in four different groups: normal geometry, concentric remodelling, concentric hypertrophy, and eccentric hypertrophy. RESULTS: Mean age was 68 years (57-74.25; 51.5% male). Comparing the four groups, significant differences were found for the five 3D-WMT-derived parameters. When patients were compared with hypertensive patients with normal geometry, our finding show that: (a) LV average torsion is the only impaired parameter that is found in the LV concentric remodelling group (P < 0.05 vs. group 1); (b) there is a trend for an increase (P = 0.055) in LV average radial strain in the group with concentric hypertrophy and this increase is accompanied by a significant decrease in the remaining studied parameters (P < 0.05); and (c) in the LV eccentric hypertrophy group, there is a significant impairment in all the studied parameters (P < 0.05). CONCLUSIONS: LV adaptative response to hypertension is accompanied by a modification or even impairment, in LV myocardial deformation evaluated by 3D-WMT. This assessment might be useful to detect early and subtle deformation impairments in hypertensive patients and it could help optimize their clinical management.
Saltijeral et al. (Thu,) conducted a observational in Hypertension (n=66). Three-dimensional-wall motion tracking (3D-WMT) vs. Normal geometry was evaluated on Myocardial deformation parameters evaluated by 3D-WMT (p=<0.05). Three-dimensional wall motion tracking revealed significant myocardial deformation impairments across different left ventricular adaptative responses to hypertension compared to normal geometry (P<0.05).