Aureomycin—a New Antibiotic: Evaluation of Its Effects in Typhoid Fever, Severe Salmonella Infections and in a Case of Colon Bacillus Bacteremia

Article1 December 1948AUREOMYCIN—A NEW ANTIBIOTIC: EVALUATION OF ITS EFFECTS IN TYPHOID FEVER, SEVERE SALMONELLA INFECTIONS AND IN A CASE OF COLON BACILLUS BACTEREMIAHARVEY SHIELDS COLLINS, M.D., TOM FITE PAINE JR., M.D., EDWARD BUIST WELLS, M.D., MAXWELL FINLAND, M.D., F.A.C.P.HARVEY SHIELDS COLLINS, M.D.Search for more papers by this author, TOM FITE PAINE JR., M.D.Search for more papers by this author, EDWARD BUIST WELLS, M.D.Search for more papers by this author, MAXWELL FINLAND, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-6-1077 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere has been a notable lack of success in the treatment of typhoid fever and salmonella infections with the chemotherapeutic and antibiotic agents that are now available. This has been true even with streptomycin which is usually quite effective against the causative organisms in vitro. Moreover, the failures of streptomycin in these infections and in some others like brucellosis have not usually been associated with the appearance of highly resistant variants as they are in most other infections, nor have they generally been associated with the presence of large and inaccessible areas of suppuration. Because these infections may be quite...Bibliography1. COLLINSPAINEFINLAND HSTFM: Clinical studies with aureomycin, Trans. N. Y. Acad. Sc. In press. Google Scholar2. PAINECOLLINSFINLAND TFHSM: Bacteriologic studies on aureomycin, Jr. Bact., 1948, lvi, 489-497. CrossrefGoogle Scholar3. COLLINSWELLSPAINEFINLAND HSEBTFM: Urinary excretion of aureomycin. Preliminary report, Proc. Soc. Exper. Biol. and Med., 1948, lix. In press. Google Scholar4. COLLINSFINLAND HSM: Aureomycin treatment of urinary tract infections. Surg., Gynec., and Obst. In press. Google Scholar5. WRIGHTSANDERLOGANPRIGOTHILL LTSMMAALM: Aureomycin: A new antibiotic with viricidal properties. A preliminary report on the successful therapy in 25 cases of lymphogranuloma venereum, Jr. Am. Med. Assoc., 1948, cxxxviii, 408-412. CrossrefGoogle Scholar6. Idem. Treatment of lymphogranuloma venereum and granuloma inguinale in humans with aureomycin, Trans. N. Y. Acad. Sci. In press. Google Scholar7. BRALEYSANDERS AEM: Aureomycin in ocular infections. A preliminary report, Jr. Am. Med. Assoc., 1948, cxxxviii, 426-427. CrossrefGoogle Scholar8. COLLINSPAINEFINLAND HSTFM: Aureomycin in treatment of pneumococcal pneumonia and meningococcemia, Proc. Soc. Exper. Biol. and Med. In press. Google Scholar9. SCHOENBACHBEYERLONG EBMSPH: Pharmacological and clinical studies with aureomycin, Trans. N. Y. Acad. Sci. In press. Google Scholar10. LENNETTEMEIKELJOHNTHELEN EHGHM: Treatment of Q fever in man with aureomycin, Trans. N. Y. Acad. Sci. In press. Google Scholar11. WOODWARDSMADELLEYGREENMANKIKAR TEJEHLRDS: Preliminary report on the beneficial effect of chloromycetin in the treatment of typhoid fever, Ann. Int. Med., 1948, xxix, 131-134. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Presented, in part, at a Conference on Aureomycin sponsored by the New York Academy of Sciences, July 21, 1948. Received for publication August 21, 1948.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital and the Department of Medicine, Harvard Medical School, Boston, Massachusetts.Aided by a grant from the United States Public Health Service.†Research Fellow in Virus Diseases, National Research Council.‡Research Fellow, American College of Physicians. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEmergence of Antibiotic-Resistant BacteriaAureomycin in pediatrics: A reviewEffect of Aureomycin on the Stomach: A Gastroscopic StudyChloromycetin and aureomycin in proctologyTyphoid Enterocolitis Simulating Chronic Bacillary DysenterySTREPTOMYCIN IN THE TREATMENT OF PROTEUS VULGARIS MENINGITIS*LEON ROSOVE, M.D., F.A.C.P., HAROLD E. WEST, M.D., ALBERT G. BOWER, M.D., F.A.C.P.AUREOMYCIN IN URINARY TRACT INFECTIONS—PRELIMINARY CLINICAL REPORT*SEYMOUR W. RUBIN, M.D., ALBERT E. GOLDSTEIN, M.D.CHLOROMYCETIN IN THE TREATMENT OF TYPHOID FEVER*LEIF Y. JACOBSEN, RICHARD A. BRODERICKTreatment of Typhoid Fever with ChloromycetinAureomycin in the treatment of infectious diseasesAntibiotic Therapy of Typhoid FeverA METHOD FOR THE DETERMINATION OF AUREOMYCIN IN THE BLOOD 1 December 1948Volume 29, Issue 6Page: 1077-1092KeywordsBloodChemotherapeutic agentsDiarrheaPenicillinSalmonellaStreptococcal infectionsStreptomycinTemperatureTyphoidUrine ePublished: 1 December 2008 Issue Published: 1 December 1948 PDF downloadLoading ...