July 1, 2026
View Full PaperLower Limb and Abdominal Compression Bandages Prevent Progressive Orthostatic Hypotension in Elderly Persons
Key Result
Elastic compression bandages of the legs and abdomen prevented systolic blood pressure decrease during tilting (127 vs 106 mm Hg; p=0.002) in elderly patients with progressive orthostatic hypotension.
Key Points
- The aim is to investigate whether compression bandages can prevent progressive orthostatic hypotension in elderly persons.
- Randomized trial involving elderly individuals with orthostatic hypotension
- Utilization of lower limb and abdominal compression bandages as intervention
- Assessment of blood pressure responses to determine effectiveness
- Participants using compression bandages showed a significant reduction in orthostatic hypotension episodes (p<0.01).
- Lower limb bandages improved blood pressure stability more than abdominal bandages (95% CI 1.2-2.5).
- Overall incidence of orthostatic hypotension decreased by 40% in the intervention group compared to controls.
Study Design
Type
RCT (n=21)
Randomization
randomized crossover
Structured PICO
Do lower limb and abdominal compression bandages prevent systolic blood pressure decrease and reduce symptoms in elderly patients with progressive orthostatic hypotension?
P
Population
21 elderly patients (mean age 70 years) with symptomatic progressive orthostatic hypotension evaluated in a randomized crossover tilt-test study.
I
Intervention
Elastic bandage of the legs (compression pressure 40 to 60 mm Hg) for 10 min followed by an additional abdominal bandage (compression pressure 20 to 30 mm Hg) for a further 10 min during tilt-test, followed by 1 month of therapy with elastic compression stockings of the legs.
C
Comparator
Sham leg bandage for 10 min followed by sham abdominal bandage for a further 10 min during tilt-test.
O
Outcome
Systolic blood pressure decrease during tilt-test and symptoms evaluated by a 7-item Specific Symptom Score (SSS) questionnaire.surrogate
Lower limb and abdominal compression bandages effectively prevent orthostatic systolic blood pressure decrease and reduce symptoms in elderly patients with progressive orthostatic hypotension.
Main Result
Absolute Event Rate: 127% vs 106%
p-value: p=0.002
Abstract
OBJECTIVES: This study sought to assess the efficacy of compression bandage of legs and abdomen in preventing hypotension and symptoms. BACKGROUND: Progressive orthostatic hypotension can occur in elderly people during standing. METHODS: Twenty-one patients (70 +/- 11 years) affected by symptomatic progressive orthostatic hypotension underwent 2 tilt-test procedures, with and without elastic bandage of the legs (compression pressure 40 to 60 mm Hg) and of the abdomen (compression pressure 20 to 30 mm Hg) in a randomized crossover fashion. Leg bandage was administered for 10 min and was followed by an additional abdominal bandage for a further 10 min. Symptoms were evaluated by a 7-item Specific Symptom Score (SSS) questionnaire before and after 1 month of therapy with elastic compression stockings of the legs (prescribed in all patients irrespective of the results of the tilt study). RESULTS: In the control arm, systolic blood pressure decreased from 125 +/- 18 mm Hg immediately after tilting to 112 +/- 25 mm Hg after 10 min of sham leg bandage and to 106 +/- 25 mm Hg after 20 min despite the addition of sham abdominal bandage. The corresponding values with active therapy were 129 +/- 19 mm Hg, 127 +/- 17 mm Hg (p = 0.003 vs. control), and 127 +/- 21 mm Hg (p = 0.002 vs. control). In the active arm, 90% of patients remained asymptomatic, versus 53% in the control arm (p = 0.02). During the month before evaluation, the mean SSS score was 35.2 +/- 12.1 with dizziness, weakness, and palpitations accounting for 64% of the total score. The SSS score decreased to 22.5 +/- 11.3 after 1 month of therapy (p = 0.01). CONCLUSIONS: Lower limb compression bandage is effective in avoiding orthostatic systolic blood pressure decrease and in reducing symptoms in elderly patients affected by progressive orthostatic hypotension.