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Hen oviduct RNA can direct the synthesis of the major oviduct protein, ovalbumin, in a cell-free system derived from rabbit reticulocytes. The protein was identified by precipitation with anti-ovalbumin, migration on gel electrophoresis, and ion exchange chromatography of tryptic peptides. Ovalbumin messenger RNA activity appears to sediment in a sucrose gradient on the low molecular weight side of the 18 S ribosomal RNA.
Rhoads et al. (Wed,) studied this question.