The Functional Consequences of Coronary Occlusion

Article1 August 1945THE FUNCTIONAL CONSEQUENCES OF CORONARY OCCLUSIONCARL J. WIGGERS, M.D., D.SC., F.A.C.P.CARL J. WIGGERS, M.D., D.SC., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-23-2-158 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe symptomatology of acute coronary occlusion is too well-known to require detailed redescription. Let it suffice for our purpose to recall three outstanding phenomena, so serious for the patient and so informative for the physician in formulating a diagnosis:1, the agonizing pain, crescendo in character and radiating from a focal region over the sternum outward to the left arm, upward to the throat, and downward to the epigastrium;2, the irregular or rapid action of the heart; and3, the signs of cardiovascular failure, such as hypotension, feeble pulse, venous congestion, cutaneous pallor, sweating, cyanosis, etc., which frequently raise...Bibliography1. TENNANT R: Factors concerned in the arrest of contraction in an ischemic myocardial area, Am. Jr. Physiol., 1935, cxiii, 677. CrossrefGoogle Scholar2. TENNANTWIGGERS RCJ: The effect of coronary occlusion on myocardial contractions, Am. Jr. Physiol., 1935, cxii, 351. CrossrefGoogle Scholar3. GUBNERCRAWFORD RJH: Roentgenkymographic studies of myocardial infarction, Am. Heart Jr., 1938, xviii, 8. Google Scholar4. SUSSMANDACKMASTER MSAM: The roentgenkymogram in myocardial infarction, Am. Heart Jr., 1940, xviv, 453. CrossrefGoogle Scholar5. MASTERGUBNERDACKJAFFE AMRSHL: The diagnosis of coronary occlusion and myocardial infarction by fluoroscopic examination, Am. Heart Jr., 1940, xx, 475. CrossrefGoogle Scholar6. WIGGERSGREEN CJHD: The ineffectiveness of drugs upon collateral flow after experimental coronary occlusion in dogs, Am. Heart Jr., 1936, xi, 527. CrossrefGoogle Scholar7. MAUTZGREGG FRDR: Dynamics of collateral circulation following chronic occlusion of coronary arteries, Proc. Soc. Exper. Biol. and Med., 1937, xxxvi, 797. CrossrefGoogle Scholar8. WEARN JTFor recent review see : Morphological and functional alterations of the coronary circulation, Harvey Lectures, 1940, xxxv, 243. Google Scholar9. ORIAS O: The dynamic changes in the ventricles following ligation of the ramus descendens anterior, Am. Jr. Physiol., 1932, c, 629. CrossrefGoogle Scholar10. WIGGERS CJ For details see : Physiology in health and disease, 4th ed., 1944, Lea and Febiger, Philadelphia, p. 671. Google Scholar11. WIGGERSWEGRIAPINERA CJRB: The effects of myocardial ischemia on the fibrillation threshold. The mechanism of spontaneous fibrillation following coronary occlusion, Am. Jr. Physiol., 1940, cxxxi, 309. CrossrefGoogle Scholar12. HARRISGUEVARA ROJAS ASA: The initiation of ventricular fibrillation due to coronary occlusion, Exper. Med. and Surg., 1943, i, 105. Google Scholar13. WIGGERS CJ After : Physiology in health and disease, 4th ed., 1944, Lea and Febiger, Philadelphia, p. 726. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Read at the Regional Meeting of the American College of Physicians in Pittsburgh, November 11, 1944.From the Department of Physiology, Western Reserve University. 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Coronarinsuffizienz, Angina pectoris und HerzinfarktDisturbances of rate, rhythm and conduction in acute myocardial infarctionAngina pectoris and congestive failureWork capacity of the left ventricle following ligation of the coronary arteryHEMODYNAMIC CHANGES FOLLOWING ACUTE MYOCARDIAL INFARCTION USING THE DYE INJECTION METHOD FOR CARDIAC OUTPUT DETERMINATION*JAMES F. GAMMILL, M.D., J. JERROLD APPLEGARTH, M.D., CHARLES E. REED, M.D., JOHN D. FERNALD, M.D., ARTHUR J. ANTENUCCI, M.D., F.A.C.P.Present-Day Concepts of ShockThe Henry Jackson Memorial LectureThe causes and mechanisms of abdominal pain 1 August 1945Volume 23, Issue 2Page: 158-169KeywordsHeart failureHeart rateHypotensionPainPharynxSternum ePublished: 1 December 2008 Issue Published: 1 August 1945 PDF downloadLoading ...