July 1, 1941

Myasthenia Gravis; A Discussion, With Presentation of a Case Associated With a Thymoma

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Case Reports1 July 1941MYASTHENIA GRAVIS; A DISCUSSION, WITH PRESENTATION OF A CASE ASSOCIATED WITH A THYMOMASAMUEL F. ARONSONSAMUEL F. ARONSONSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-1-137 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMyasthenia gravis, a symptom-complex manifested by an incapacity of one or more groups of voluntary muscles for sustained effort, is without any demonstrable involvement of the nervous system.Thomas Willis is credited by several authors1, 2with having first described the disease; but Wechsler3claims that Wilkes in 1877 deserves that credit. Erb1gave a clear and classical description in 1878 but believed that the condition was due to pathological changes in the central nervous system. Oppenheim4claimed credit for first clearly differentiating the disease in 1887 and named it bulbar paralysis without pathological lesions. Jolly,2in 1895, demonstrated, by...Bibliography1. GARRISON FH: History of medicine, 4th Edition, 1929, W. B. Saunders, Philadelphia. Google Scholar2. VIETSSCHWAB HRRS: Diagnosis and treatment of myasthenia gravis, with special reference to use of prostigmine, Jr. Am. Med. Assoc., 1939, cxiii, 559-563. CrossrefGoogle Scholar3. WECHSLER IS: Text-book of clinical neurology, 3rd Edition, 1935, W. B. Saunders, Philadelphia. Google Scholar4. OPPENHEIM H: Text-book of nervous diseases, Vol. 2, 1911, J. B. Lippincott, Philadelphia. Google Scholar5. DAY AB: Myasthenia gravis; recent developments in treatment; report of case, Jr. Missouri Med. Assoc., 1939, xxxvi, 243-245. Google Scholar6. NORRIS EH: Thymoma and thymic hyperplasia in myasthenia gravis with observations on general pathology, Am. Jr. Cancer, 1936, xxvii, 421-433. CrossrefGoogle Scholar7. 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Author, Article, and Disclosure InformationAffiliations: Camp Murray, Washington*Received for publication August 26, 1940. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThymoma: With a report of 5 casesMyasthenia Gravis and the Thymus A Survey and the Case of a 9-Year-old GirlCYSTIC TUMOR OF THE THYMIC REGION AND MYASTHENIA GRAVIS: REPORT OF A CASE IN WHICH THE TUMOR WAS REMOVED*CHARLES B. FULGHUM, M.D., F.A.C.P. 1 July 1941Volume 15, Issue 1Page: 137-145KeywordsCentral nervous systemLesionsMusclesMyasthenia gravisNervous systemNeuromuscular diseasesParalysisThymoma ePublished: 1 December 2008 Issue Published: 1 July 1941 PDF downloadLoading ...

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