This review provides pragmatic approaches for individualized decision-making regarding hemostatic therapy and reperfusion strategies in acute stroke patients taking dabigatran.
This review provides pragmatic approaches for individualized decision-making regarding hemostatic therapy and reperfusion strategies in acute stroke patients taking dabigatran.
Dabigatran etexilate is emerging as an alternative for vitamin K antagonists, but evidence-based guidelines for management of intracerebral hemorrhage and acute ischemic stroke in patients taking this drug are nonexistent. This review summarizes current knowledge on key pharmacological features and the assessment of dabigatran activity. Pragmatic approaches are provided for individualized decision taking with regard to hemostatic therapy and reperfusion strategies in acute stroke patients.
Brouns et al. (2012) conducted a review in Acute stroke (intracerebral hemorrhage and acute ischemic stroke) in patients taking dabigatran. Hemostatic therapy and reperfusion strategies was evaluated. This review provides pragmatic approaches for individualized decision-making regarding hemostatic therapy and reperfusion strategies in acute stroke patients taking dabigatran.