Serial Prothrombin Estimations in Cardiac Patients: Diagnostic and Therapeutic Implications; Use of Dicumarol

Article1 April 1946SERIAL PROTHROMBIN ESTIMATIONS IN CARDIAC PATIENTS: DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS; USE OF DICUMAROLERNEST COTLOVE, M.D., JEFFERSON J. VORZIMER, M.D., F.A.C.P.ERNEST COTLOVE, M.D.Search for more papers by this author, JEFFERSON J. VORZIMER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-4-648 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptVenous thrombosis with pulmonary embolism has long been recognized as an important and serious complication in postoperative surgical patients. The significance of thromboembolism in medical patients and particularly in those with heart disease is only beginning to gain adequate recognition. Pathological studies1, 2 have shown pulmonary embolism to be the main or contributory cause of death in one-fourth to one-third of patients dying with coronary occlusion or congestive heart failure.White3has recently summarized the significance of thromboembolism in heart disease. Pulmonary embolism may simulate heart disease, especially myocardial infarction; it may precipitate a severe anginal attack or even myocardial...Bibliography1. EPPINGERKENNEDY ECJA: The cause of death in coronary thrombosis, with special reference to pulmonary embolism, Am. Jr. Med. Sci., 1938, cxcv, 104-106. CrossrefGoogle Scholar2. WILLIAMSRAINEY RHJ: Cause of death in patients with congestive heart failure, Am. Heart Jr., 1938, xv, 385-394. CrossrefGoogle Scholar3. WHITE PD: Heart disease, 3rd Edition, 1944, Macmillan Co., New York, N. Y. Google Scholar4. HUNTERSNEEDENROBERTSONSNYDER WCVDTDGA: Thrombosis of the deep veins of the leg, Arch. Int. Med., 1941, lxviii, 1-17. CrossrefGoogle Scholar5. 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HOMANS J: Deep quiet venous thrombosis in the lower limb, Surg., Gynec., and Obst., 1944, lxxix, 70-82. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication February 9, 1945.From the Medical, Surgical, Urological, Gynecological and Obstetrical Services of Beth Israel Hospital, New York City.†"Dicumarol" is the registered collective trade-mark adopted by the Wisconsin Alumni Research Foundation for the synthetic preparation 3, 3′-methylenebis (4-hydroxycoumarin). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAnalysis of the first therapeutic-target-achieving time of warfarin therapy and associated factors in patients with pulmonary embolismEffect of diseases on response to vitamin K antagonistsChanges in Warfarin Sensitivity During Decompensated Heart Failure and Chronic Obstructive Pulmonary DiseaseDoes heart failure exacerbation increase response to warfarin?A critical review of the literaturePathophysiology of Acute Myocardial Infarction, 1981PHILIP B. OLIVA, M.D.Coagulability of Blood in Acute Myocardial InfarctionKreislaufdynamik, Gerinnungspotential und ThromboseThromboembolic phenomena associated with rapid diuresis in the treatment of congestive heart failureThe Prediction of ThromboembolismPlasma prothrombin times in normal human subjects. The effect of certain factors on the prothrombin timeEstimation of Prothrombin in Dicoumarin TherapyDicumarol Therapy in Congestive Heart FailureVenous thrombosis and pulmonary embolism in tuberculosisPresent status of the problem of thromboembolismHematologyIncidence of thrombo-embolic lesions accompanying myocardial infarctionRecent Advances in Hematology 1 April 1946Volume 24, Issue 4Page: 648-665KeywordsAlumniCardiovascular therapyHeart failureLongitudinal studiesMyocardial infarctionObstetrics and gynecologyPulmonary embolismThromboembolismThrombosis Issue Published: 1 April 1946 PDF downloadLoading ...