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Arginine NO-hydroxylase N&-Hydroxyarginine mono-oxygenase NADPH diaphorase Cytochrome c reductase NADPH oxidase 5 Dihydropteridine reductase Arg + NADPH + H+ + 02 -+ HydroxyArg + NADP+ + H20 HydroxyArg + 1(NADPH + H+) + 02 -+ Cit + NO + H20 NitroBlue Tetrazolium (NBT) + NADPH + H+ Reduced NBT + NADP+ Cyt c+ NADPH + H+ -+ Reduced cyt c+ NADP+ NADPH + H+ + 02 H202 + NADP+ 1NADPH + 02 -+ 02 + 1(NADP+
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Richard G. Knowles
Stevenage Bioscience Catalyst
Salvador Moncada
University College Dublin
Biochemical Journal
Wellcome Trust
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Knowles et al. (Tue,) studied this question.
synapsesocial.com/papers/6a11e43c71528255b221bc55 — DOI: https://doi.org/10.1042/bj2980249