Highlights the expanding role of transgenic and gene-targeting technology in studying renal physiology in mouse models.
As the transgenic and gene-targeting technology has become an invaluable experimental approach to study the function of gene products, the need has been expanded to assess the physiology in the mouse, which is virtually the only animal species to which that new genetic technology can apply. In this regard, renal physiologists have also received fruits of success from modern technology in several key areas, and areas are expanding in both depth and scope.
Meneton et al. (Wed,) studied this question.