30,000 Swedish men and women aged between 50 and 64 years
Extensive characterization using new imaging technologies, large-scale 'omics', and epidemiological analyses
Improvement of risk prediction for cardiopulmonary diseases and optimization of the ability to study disease mechanisms
The SCAPIS study design outlines a comprehensive approach using advanced imaging and omics in 30,000 Swedish individuals to improve cardiopulmonary risk prediction and understand disease mechanisms.
Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started.
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Göran Bergström
Cardiac Imaging
G Berglund
Preventive Cardiology
Anders Blomberg
Umeå University
Journal of Internal Medicine
Karolinska Institutet
Lund University
Uppsala University
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Bergström et al. (Fri,) studied this question.
synapsesocial.com/papers/69d56c1e75589c71d767cbca — DOI: https://doi.org/10.1111/joim.12384
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