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Summary Purified human antidextran, an S = 7 γ-globulin, was about 1000 to 3000 times less potent in sensitizing intestine in vitro and 25 to 100 times less effective in sensitizing for passive cutaneous anaphylaxis than were the most potent human diphtheria antitoxic sera under the conditions studied. Human antitoxic sera also varied as much as 100-fold in their sensitizing capacity for intestine/µg antitoxin N.
Kabat et al. (1963) studied this question.