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Endogenous estrogen levels were inversely, and SHBG levels positively, associated with colorectal cancer risk, even after control for several colorectal cancer risk factors. These results suggest that endogenous estrogens may confer protection against colorectal tumorigenesis among postmenopausal women.
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Neil Murphy
Jet Propulsion Laboratory
Howard D. Strickler
Albert Einstein College of Medicine
Frank Z. Stanczyk
University of Southern California
JNCI Journal of the National Cancer Institute
Imperial College London
University of Southern California
Fred Hutch Cancer Center
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Murphy et al. (Sat,) studied this question.
synapsesocial.com/papers/69dff6591827a1d0b1255874 — DOI: https://doi.org/10.1093/jnci/djv210