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These data indicate that the capacities to clear 5-FU are lower in women compared with men and are not influenced by age. It would be of interest to know whether this sex-related difference in 5-FU Cl may be clinically relevant by considering both toxicity and tumor response to 5-FU treatment.
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G. Milano
M C Etienne
E. Cassuto‐Viguier
Journal of Clinical Oncology
Centre Antoine Lacassagne
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Milano et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69dbe44740b636d1dda3c316 — DOI: https://doi.org/10.1200/jco.1992.10.7.1171