Right ventricular apex pacing resulted in a significantly longer paced QRS duration compared with outflow and inflow areas (160 ± 15 ms vs 140 ± 15 ms, P=0.02, and vs 133 ± 17 ms, P<0.001).
Observational (n=50)
Does the anatomical location of the right ventricular pacing site affect paced QRS duration in patients implanted with pacemakers?
Right ventricular pacing at the apex results in a significantly longer paced QRS duration compared to outflow and inflow areas, suggesting alternative sites may produce more physiological ventricular activation.
Absolute Event Rate: 160% vs 140%
p-value: p=0.02
BACKGROUND: The relationship between the anatomical location of right ventricular pacing site and paced QRS duration is unclear. In this study, we aimed to investigate the relationship between right ventricular pacing site and paced QRS duration using cardiac angiography. METHODS: Fifty patients were implanted with pacemakers. The right ventricular lead position was determined from the findings of cardiac angiography and the paced QRS duration was measured. Cardiac angiography was used to display the right ventriculogram (RVG) and the left ventriculogram (LVG). The RVG view was divided into three areas and the LVG view was divided into four areas. RESULTS: The paced QRS duration value was significantly longer in the right ventricular apex area compared with the outflow and inflow areas (160 ± 15 ms vs 140 ± 15 ms, P = 0.02, and vs 133 ± 17 ms, P < 0.001, respectively), but those values were not statistically significantly different between the right ventricular outflow and the right ventricular inflow areas (140 ± 15 ms vs 133 ± 17 ms, P = 0.187). When assessed with LVG views, there were the statistically significant differences in the paced QRS duration values in all areas except the apex area. (LV mid-anterior: 147 ± 11 ms vs LV base: 127 ± 13 ms, P < 0.001, and vs LV mid-septum: 129 ± 12 ms, P = 0.001, respectively.) CONCLUSIONS: Cardiac angiography showed that there was a relationship between the anatomical right ventricular pacing site and paced QRS duration. Cardiac angiography can help determine the areas that produce shorter paced QRS duration.
Kawakami et al. (Tue,) conducted a observational in Patients implanted with pacemakers (n=50). Right ventricular apex pacing vs. Right ventricular outflow and inflow pacing was evaluated on Paced QRS duration (p=0.02). Right ventricular apex pacing resulted in a significantly longer paced QRS duration compared with outflow and inflow areas (160 ± 15 ms vs 140 ± 15 ms, P=0.02, and vs 133 ± 17 ms, P<0.001).
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