June 1, 1998
View Full PaperClinical Significance of Cytogenetic Abnormalities in Adult Acute Lymphoblastic Leukemia
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Abstract
ACUTE LYMPHOBLASTIC leukemias (ALL) are characterized by clonal proliferation, accumulation, and tissue infiltration of neoplastic cells. They are mainly regarded as childhood diseases, with an early incidence peak at 2 to 5 years of age, where they represent about 80% of the childhood leukemias in