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Abstract The choice of statistical method can greatly influence the calculated normal range apart from any biological or chemical considerations. Nonparametric normal range estimates are, for practical purposes, as accurate as estimates that assume the distribution of data to be gaussian or loggaussian when the distribution assumed is true. When data are not distributed as assumed, nonparametric estimates are more accurate.
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Allen H. Reed
Stennis Space Center
Richard J. Henry
Poole Hospital
William B. Mason
Henry Ford Hospital
Clinical Chemistry
BioScience Laboratories (United States)
Bio-Rad (United States)
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Reed et al. (Thu,) studied this question.
synapsesocial.com/papers/6a1f07ea459b8c409ce6c101 — DOI: https://doi.org/10.1093/clinchem/17.4.275