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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency | Synapse

May 30, 2015New England Journal of Medicine9,556 citationsOpen Access

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

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DLDung T. Le JUJennifer N. Uram HWHao Wang

Key Points

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Abstract

This study showed that mismatch-repair status predicted clinical benefit of immune checkpoint blockade with pembrolizumab. (Funded by Johns Hopkins University and others; ClinicalTrials.gov number, NCT01876511.).

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Cite This Study

Le et al. (2015) studied this question.

synapsesocial.com/papers/694d993685397a08abacbda6 https://doi.org/https://doi.org/10.1056/nejmoa1500596

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