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Splice junction sequences from a large number of nuclear and viral genes encoding protein have been collected. The sequence CAAG/GTAGAGT was found to be a consensus of 139 exon-intron boundaries (or donor sequences) and (TC)nNCTAG/G was found to be a consensus of 130 intron-exon boundaries (or acceptor sequences). The possible role of splice junction sequences as signals for processing is discussed.
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Stephen M. Mount (Fri,) studied this question.
synapsesocial.com/papers/69df7bd7c51a1f47d47a11e0 — DOI: https://doi.org/10.1093/nar/10.2.459
Stephen M. Mount
University of Maryland, College Park
Nucleic Acids Research
Yale University
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