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Although clinical research often tries to reduce and simplify reality to be able to study its essential elements, it is increasingly recognized that in practice many health care interventions are complex. Therefore, this month's issue of the Journal of Clinical Epidemiology presents a timely series on considering complexity in systematic reviews of interventions. Anderson et al. provide a brief introduction to complexity thinking and how this relates to simple and complicated interventions. They provide an overview of the seven original articles included in this series.
Tugwell et al. (Tue,) studied this question.