Do thermodynamic perfusion variables (SW and LVP) better predict perfusion and outcome compared to purely flow-derived variables during resuscitation?
Thermodynamic perfusion variables such as stroke work and left ventricular power may provide better thresholds for evaluating hemodynamic performance during resuscitation than flow-derived variables alone.
Thermodynamic perfusion variables that encompass both pressure and flow, such as SW and LVP, are more closely related to perfusion and outcome than the purely flow-derived variables. The higher SW and LVP in survivors is related to better ventricular-arterial coupling, and therefore more efficient cardiac function. Cutoff values for LVP of 320 mm Hg x L x min(-1) x m(-2) and for SW of 4,000 mm Hg x mL x m(-2) may be useful thresholds for evaluating hemodynamic performance during resuscitation.
Chang et al. (1998) studied this question.