July 1, 1958
View Full PaperPulsus Alternans in Aortic Stenosis
Structured PICO
P
Population
Patients with acquired aortic stenosis and patients with congenital aortic stenosis of similar severity
O
Outcome
Frequency of pulsus alternans and the product of left ventricular systolic pressure and heart ratesurrogate
Pulsus alternans is more common in acquired than congenital aortic stenosis and is associated with a higher myocardial oxygen requirement index.
Abstract
Alternation in the strength of left ventricular contractions was noted relatively frequently in patients with acquired aortic stenosis, but not in patients with congenital aortic stenosis of similar severity. The product of left ventricular systolic pressure and heart rate, an index of the myocardial oxygen requirement, was significantly higher in those patients who exhibited persistent pulsus alternans.