June 3, 2013Open Access

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

Key Points

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Abstract

Key Points AML blasts have an arginase-dependent ability to inhibit T-cell proliferation and hematopoietic stem cells. AML blasts have an arginase-dependent ability to modulate the polarization of monocytes.

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

Key Points

Abstract

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