Catheter ablation of ventricular tachycardia was associated with a lower rate of VT/VF recurrence in patients with ARVC compared to those with NIDCM (p<0.05).
Cohort (n=88)
Does the underlying structural heart disease affect long-term outcomes after catheter ablation of ventricular tachycardia?
Long-term outcomes of ventricular tachycardia ablation vary significantly by underlying structural heart disease, with ARVC patients demonstrating a better prognosis than those with dilated cardiomyopathy.
p-value: p=<0.05
BACKGROUND: Catheter ablation of ventricular tachycardia (VT) is feasible. However, the long-term outcomes for different underlying diseases have not been well defined. METHODS: Eighty-eight consecutive patients who underwent catheter ablation of VT using a three-dimensional mapping system were analyzed. The primary endpoint was any VT or ventricular fibrillation (VF) recurrence. Secondary endpoints were a composite of death or any VT/VF recurrence. Underlying heart diseases were remote myocardial infarction (remote MI) in 51 patients and non-ischemic cardiomyopathy in 37 (arrhythmogenic right ventricular cardiomyopathy ARVC in 18 patients, and dilated cardiomyopathy NIDCM in 19). RESULTS: Acute success was achieved in 82 of 88 (93%) patients. During a follow-up period of 39.2±4.6 months, VT recurred in 26 of 87 (30%), and VT/VF recurrence or death occurred in 39 of 87 (45%) patients. ARVC had better outcomes than NIDCM for the primary (p<0.05) and secondary endpoints (p<0.05). Remote MI-VT revealed a midrange outcome. CONCLUSIONS: The long-term outcomes after catheter ablation of VT varied according to the underlying heart disease. ARVC-VT ablation was associated with better long-term prognosis than NIDCM. Remote MI-VT demonstrated a midrange outcome.
Goya et al. (2014) conducted a cohort in Ventricular tachycardia in patients with structural heart disease (n=88). Catheter ablation of ventricular tachycardia vs. Underlying heart disease (ARVC vs NIDCM vs remote MI) was evaluated on Any VT or ventricular fibrillation (VF) recurrence (p=<0.05). Catheter ablation of ventricular tachycardia was associated with a lower rate of VT/VF recurrence in patients with ARVC compared to those with NIDCM (p<0.05).