Patients with affective disorders had significantly higher mortality rates from natural and unnatural causes compared to the age- and gender-matched general population.
Cohort (n=54,103)
Does first-time admission for affective disorder increase the risk of mortality and suicide compared to the general population?
Patients with affective disorders have an elevated risk of mortality from both natural and unnatural causes, with an increasing risk of suicide early after first admission.
BACKGROUND: The high mortality from suicide in patients admitted to hospital with an affective disorder is well documented, although specific causes of mortality and changes in mortality are less well studied. AIMS: To describe the pattern of mortality in patients with affective disorder and to study changes in suicide risk during the study period. METHOD: All patients (n = 54,103) admitted for the first time to a psychiatric hospital in Denmark during the period 1973-1993 because of affective disorder were included in this study. The mortality rate was compared with that of the general population. RESULTS: Mortality from natural and unnatural causes was elevated in all subgroups of affective disorder. The risk of suicide among patients ill for one year or less after first admission increased during the period 1973-1993. CONCLUSIONS: More attention should be paid to the risk of suicide and to physical illness in patients with affective disorders.
Høyer et al. (Sat,) conducted a cohort in Affective disorders (n=54,103). Affective disorders vs. General population was evaluated on Mortality (natural and unnatural causes). Patients with affective disorders had significantly higher mortality rates from natural and unnatural causes compared to the age- and gender-matched general population.
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