Is the level of systemic inflammation associated with mortality in patients after out-of-hospital cardiac arrest?
Higher levels of systemic inflammation markers (IL-6 and procalcitonin) at 24 hours post-arrest are independently associated with increased mortality in out-of-hospital cardiac arrest patients.
Level of inflammation, assessed by interleukin-6 and procalcitonin, was independently associated with increased mortality with the highest discriminative value obtained 24 hours after out-of-hospital cardiac arrest. Interventions aiming at decreasing level of inflammation as a way to improve outcome may be investigated in future studies.
Bro‐Jeppesen et al. (Tue,) studied this question.