Obesity was associated with a 62% lower likelihood of blood pressure control (OR 0.38; 95% CI 0.19-0.75) compared with lean/normal-weight status, despite a higher rate of treatment.
Cross-Sectional (n=2,075)
Yes
Does obesity reduce blood pressure control in hypertensive adults compared to lean/normal-weight individuals?
Obese individuals have a higher prevalence of hypertension and receive more treatment, but have significantly worse blood pressure control compared to lean individuals.
Effect estimate: OR 0.38 (95% CI 0.19-0.75)
OBJECTIVE: We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS: Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carried out in 2006-2007. BP was measured three times on the left arm using an automatic device. Weight and height were assessed using standardized methods to compute body mass index (BMI, kg/m(2)). BP-lowering drugs were self-reported. BP control was defined as SBP/DBP less than 140/90 among hypertensive individuals. RESULTS: As anticipated, mean SBP and DBP increased significantly across BMI categories (P for trend <0.0001). The age-adjusted and sex-adjusted prevalence of hypertension also increased across the same categories (15.7, 24.7 and 56.9%, respectively, P < 0.001). Among hypertensive individuals, obese participants were more likely to receive BP-lowering drugs compared with their lean/normal weight counterparts (P = 0.02). However, independently of age, smoking status and alcohol intake, obesity was associated with a 62% lower risk of BP control (OR: 0.38, 95% CI: 0.19-0.75) compared with the lean/normal-weight status. CONCLUSION: Although hypertension was much more prevalent in the obese compared with overweight and lean/normal-weight individuals, uncontrolled hypertension was also more frequent despite a higher rate of treatment. To some extent, this observation may probably be the consequence of obesity and its complex pathophysiology, more than to an inadequate therapeutic decision by clinicians.
Czernichow et al. (Tue,) conducted a cross-sectional in Hypertension and Obesity (n=2,075). Obesity vs. Lean/normal-weight status was evaluated on Blood pressure control (SBP/DBP <140/90) (OR 0.38, 95% CI 0.19-0.75). Obesity was associated with a 62% lower likelihood of blood pressure control (OR 0.38; 95% CI 0.19-0.75) compared with lean/normal-weight status, despite a higher rate of treatment.