August 14, 2006Canadian Medical Association Journal137 citationsOpen Access

Is there another way to take account of noncompliance in randomized controlled trials?

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Abstract

Noncompliance is an important issue in the design and conduct of randomized controlled trials (RCTs). It arises when participants do not receive the treatment or intervention to which they were randomly allocated. For example, some participants invited to go through a screening program may not

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Cite This Study

Catherine Hewitt (2006) studied this question.

synapsesocial.com/papers/6a6f3d395d37378ac1dc507a https://doi.org/10.1503/cmaj.051625

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1RANDOMISED, CONTROLLED TRIAL OF FAECAL OCCULT BLOOD SCREENING FOR COLORECTAL CANCER1989 · 535 citations
2ADJUSTING FOR NON-COMPLIANCE AND CONTAMINATION IN RANDOMIZED CLINICAL TRIALS1997 · 310 citations
3Randomised controlled trial of faecal-occult-blood screening for colorectal cancer1996 · 2,813 citations
4Estimating treatment effects from randomized clinical trials with noncompliance and loss to follow-up: the role of instrumental variable methods2005 · 211 citations
5The classification of cancer of the rectum1932 · 1,518 citations

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