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Palladium-Catalyzed Stereocontrolled Vinylation of Azoles and Phenothiazine | Synapse

January 24, 2002

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Palladium-Catalyzed Stereocontrolled Vinylation of Azoles and Phenothiazine

ALArtem Y. LebedevLomonosov Moscow State University VIVyatcheslav V. IzmerLomonosov Moscow State University DKDenis N. Kazyul'kinLomonosov Moscow State University

Key Points

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Abstract

reaction: see text Vinylation of various azoles (pyrrole, indole, carbazole, and their derivatives) and phenothiazine with vinyl bromides catalyzed by palladium-phosphine complexes results in the respective N-vinylazoles in 30-99% yields. This reaction with cis- and trans-beta-bromostyrenes is stereospecific giving the respective products with full retention of configuration.

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Cite This Study

Lebedev et al. (Thu,) studied this question.

synapsesocial.com/papers/69de6b7abf539e227055889a https://doi.org/https://doi.org/10.1021/ol0172370

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