Healing canine infarcts
Correlation of Connexin43 gap junction distribution with the location of reentrant circuits in the epicardial border zonesurrogate
Disturbed Connexin43 gap junction distribution correlates with reentrant VT circuit locations in healing canine infarcts, suggesting it plays a role in VT susceptibility.
Altered gap-junctional distribution is part of the early remodeling of myocardium after infarction, and by defining the location of the common central pathway of the reentrant VT circuits, it may be a determinant of VT susceptibility.
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Nicholas S. Peters
Electrophysiology
James Coromilas
Electrophysiology
Nicholas J. Severs
Electrophysiology
Circulation
St Mary's Hospital
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Peters et al. (Tue,) studied this question.
synapsesocial.com/papers/69d56e1d75589c71d767d3d9 — DOI: https://doi.org/10.1161/01.cir.95.4.988