Disturbed Connexin43 gap junction distribution correlates with reentrant VT circuit locations in healing canine infarcts, suggesting it plays a role in VT susceptibility.
Altered gap-junctional distribution is part of the early remodeling of myocardium after infarction, and by defining the location of the common central pathway of the reentrant VT circuits, it may be a determinant of VT susceptibility.
Peters et al. (1997) studied this question.