Electrophysiology
VT, VF, and sudden cardiac death prevention
Also called VT, ventricular tachycardia, VF, ventricular fibrillation
Sources: updated Oct 5, 2026
Specific, answerable questions in this area — each with its own synthesized evidence and consensus. Open one to see the forest plot, source trials, and how the consensus has changed over time.
Does eplerenone vs spironolactone improve All-Cause Mortality in Heart failure?
Low CertaintySupports benefiteplerenone vs Spironolactone · All-Cause Mortality
Does amiodarone vs placebo improve Sustained Ventricular Tachycardia in Wolff-Parkinson-White Syndrome?
Low Certaintyamiodarone vs placebo · Sustained Ventricular Tachycardia
Synthesized from 2 evidence-backed clinical questions on Ventricular arrhythmias — 1 supports benefit, 1 no benefit shown.
No clear lean — the placed evidence is contested
1
Favor benefit
50% of all
1
No benefit shown
50% of all
Low certainty on 100% of questions
Does eplerenone vs spironolactone improve All-Cause Mortality in Heart failure?
Low Certainty+ Favors benefiteplerenone vs Spironolactone · All-Cause Mortality
3 studies (34,178 patients) provide low-certainty evidence for benefit of eplerenone for All-Cause Mortality in Heart failure.
Does amiodarone vs placebo improve Sustained Ventricular Tachycardia in Wolff-Parkinson-White Syndrome?
Low Certainty− No benefit shownamiodarone vs placebo · Sustained Ventricular Tachycardia
3 studies (36 patients) provide low-certainty evidence against benefit of amiodarone for Sustained Ventricular Tachycardia in Wolff-Parkinson-White Syndrome.
A clinical question appears here only when its condition matches this topic, an outcome and a comparator were extracted from the studies, at least two studies and a patient count are on file, and the certainty is low or higher.
Supports benefit, no benefit shown, and mixed describe the direction of the measured effect. No benefit shown means the evidence does not support a benefit. It is not a finding of harm. Too little evidence means the question did not clear that bar.
Study count, RCT count, and patient count are separate. The patient total adds only studies that are linked into a study family and whose sample size is not flagged as implausible. A reversal is listed only when at least one randomized trial sits on each side of the change.
The overview is drafted from the guideline recommendations, trials, papers, and questions on this page, and every sentence has to cite one of them. It stays unverified until an NPI-verified clinician or a Synapse admin approves it. Approving records that person's name.
Seoul National University
h-index 214 · 316k citations
Most-cited researchers publishing on Ventricular arrhythmias.
