Evidence library
Each topic aggregates the latest peer-reviewed papers with AI-enriched clinical evidence, structured PICO analysis, consensus synthesis, and guideline context.
Synapse indexes over 600,000 peer-reviewed medical research papers with AI-enriched clinical evidence, PICO-structured analysis, and methodology classification. Browse topics below to find the latest research in each area of cardiology.
AF management, anticoagulation, and rhythm control
ElectrophysiologyCatheter ablation efficacy and long-term results
ElectrophysiologyTreatment strategies for persistent atrial fibrillation
ElectrophysiologyVT, VF, and sudden cardiac death prevention
ElectrophysiologyPacemakers, ICDs, and CRT outcomes
ElectrophysiologyDOACs vs warfarin, bleeding risk, and stroke prevention
ElectrophysiologyCAD diagnosis, treatment, and outcomes
Interventional CardiologyPCI techniques, stents, and outcomes
Interventional CardiologyST-elevation MI treatment and primary PCI
Interventional CardiologyCTO intervention techniques and outcomes
Interventional CardiologyDAPT duration and strategies post-PCI
Interventional CardiologyTAVR techniques, outcomes, and patient selection
Structural HeartTAVR outcomes and durability in low surgical risk
Structural HeartMitral repair, replacement, and transcatheter therapies
Structural HeartTR management and emerging transcatheter options
Structural HeartLAAC devices and outcomes vs anticoagulation
Structural HeartAortic stenosis, mitral regurgitation, and valve management
Structural HeartCholesterol treatment and ASCVD risk reduction
Prevention & LipidsPCSK9i efficacy, outcomes, and cost-effectiveness
Prevention & LipidsStatin efficacy, safety, and optimal intensity
Prevention & LipidsBlood pressure targets and treatment strategies
Prevention & LipidsPrimary and secondary prevention strategies
Prevention & LipidsGLP-1 RA effects on CV events and mortality
Prevention & LipidsEchocardiography, CT, MRI, and nuclear imaging
Cardiac ImagingEcho techniques, strain imaging, and applications
Cardiac ImagingCCTA for CAD diagnosis and risk stratification
Cardiac ImagingCMR applications in cardiomyopathy and viability
Cardiac ImagingHCM, DCM, and other cardiomyopathies
General CardiologyHCM management, screening, and emerging therapies
General CardiologyMyocarditis diagnosis, treatment, and outcomes
General CardiologyATTR and AL amyloid cardiomyopathy
General CardiologyPericarditis, pericardial effusion, and constrictive disease
General CardiologyIE diagnosis, treatment, and surgical indications
General CardiologyAI/ML applications in CV diagnosis and prognosis
Other TopicsCardiovascular effects of cancer therapy
Other TopicsCV manifestations and sequelae of COVID-19
Other TopicsSex-specific cardiovascular disease and outcomes
Other TopicsAthlete heart, screening, and sudden cardiac death
Other TopicsGLP-1 receptor agonists in cardiometabolic and obesity research, including cardiovascular outcome trials and mechanistic studies.
Other TopicsPeer-reviewed research on semaglutide across obesity, type 2 diabetes, and cardiovascular outcome trials.
Other TopicsResearch on tirzepatide, a dual GIP/GLP-1 receptor agonist, including SURPASS, SURMOUNT, and cardiovascular-focused substudies.
Other TopicsEarly-phase and translational research on retatrutide, a GLP-1/GIP/glucagon tri-agonist in development for obesity and metabolic disease.
Other TopicsPreclinical and limited clinical literature on BPC-157, a synthetic pentadecapeptide studied in wound healing and GI models.
Other TopicsResearch on thymosin beta-4, an actin-binding peptide studied in tissue repair, cardiac injury models, and regenerative biology.
Other TopicsStudies on CJC-1295, a long-acting GHRH analog, in growth hormone axis and body-composition research contexts.
Other TopicsResearch on ipamorelin, a selective growth hormone secretagogue peptide, in pituitary signaling and metabolic studies.
Other TopicsClinical and translational research on tesamorelin, an FDA-approved GHRH analog for HIV-associated lipodystrophy, and related metabolic studies.
Other TopicsLiterature on sermorelin, a GHRH(1-29) analog used in growth hormone deficiency diagnostics and research settings.
Other TopicsResearch on bremelanotide (PT-141), a melanocortin receptor agonist peptide studied for hypoactive sexual desire disorder.
Other TopicsPeer-reviewed research on oxytocin in social neuroscience, obstetrics, and intranasal peptide administration studies.
Other Topics