Cardiovascular effects of cancer therapy
Also called onco-cardiology, cancer cardiotoxicity, chemotherapy heart
Sources: 12 new papers · 5 key papers · updated Oct 20, 2026
Unverified · drafted by AI from the sources cited below
Cardiotoxicity involves damage to the heart or its function secondary to exposure to toxic substances such as drugs used in chemotherapy, immunotherapy, or radiation.1
Comprehensive echocardiographic assessment is utilized to evaluate cardiac parameters before and after procedures such as allogeneic hematopoietic stem cell transplantation.1 In a cohort of 96 patients, significant changes were observed in diastolic parameters, left ventricular mass, global longitudinal strain, and right ventricular ejection fraction following transplantation.1
The impact of dimethyl sulfoxide on cardiac function during allogeneic hematopoietic stem cell transplantation remains unclear.1
The role of ASF1B in disease pathogenesis and treatment: from histone chaperone to clinical target
Cancer Biology & Therapy — Deng Y — Nov 2026
dsRNA: mechanisms of gene expression regulation, disease pathogenesis, and therapeutic potential
RNA Biology — 刘水平 — Nov 2026
Widening the BRCAness therapeutic window for its synthetic lethality effects with PARP inhibitors
Communications Biology — Fernandez A — Nov 2026
Renin–Angiotensin System Inhibitor Use and Cancer Incidence Among UK Biobank Participants: A Prospective Cohort Study
Cancer Medicine — Shi X — Nov 2026
Mechanisms of Tumor Cell Invasion: Insights From the Perspective of Epithelial‐to‐Mesenchymal Transition
Cell Biochemistry and Function — Guarino M — Nov 2026
Multi-omics survival prediction under modality incompleteness via dynamic modality graphs and product-of-experts fusion
Briefings in Bioinformatics — Xie W — Nov 2026
Frequency and Risk Factors of Cancer Therapy-Related Cardiac Dysfunction in Patients Receiving Chemotherapy: A Prospective Cohort Study at a Tertiary Centre.
La Clinica Terapeutica — Chieu L — Nov 2026
PD-(L)1×VEGF bispecific antibodies in solid tumors: clinical trial updates from ASCO 2026
Journal of Hematology & Oncology — Wang Z — Oct 2026
Clinical Significance of Indeterminate Antibody to Hepatitis C in Cancer Patients
Journal of Viral Hepatitis — Pascucci J — Oct 2026
Maximising Cancer Prevention and Early Detection in the Australian Cancer Plan: Where Are We Now and What Should Come Next?
The Medical Journal of Australia — Symonds E — Oct 2026
Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study
The Lancet — Schrag D
403 citations · 2023 · among the most cited on Cardio-oncology
The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
The Lancet — ElHafeez S
329 citations · 2025 · among the most cited on Cardio-oncology
cis-Diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: Quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatinum(II)
Fichtinger-Schepman A
264 citations · 2026 · among the most cited on Cardio-oncology
Radiotherapy toxicities: mechanisms, management, and future directions
The Lancet — Verginadis I
179 citations · 2025 · among the most cited on Cardio-oncology
Long-term care for people treated for cancer during childhood and adolescence
The Lancet — Tonorezos E
107 citations · 2022 · among the most cited on Cardio-oncology
A clinical question appears here only when its condition matches this topic, an outcome and a comparator were extracted from the studies, at least two studies and a patient count are on file, and the certainty is low or higher.
Supports benefit, no benefit shown, and mixed describe the direction of the measured effect. No benefit shown means the evidence does not support a benefit. It is not a finding of harm. Too little evidence means the question did not clear that bar.
Study count, RCT count, and patient count are separate. The patient total adds only studies that are linked into a study family and whose sample size is not flagged as implausible. A reversal is listed only when at least one randomized trial sits on each side of the change.
The overview is drafted from the guideline recommendations, trials, papers, and questions on this page, and every sentence has to cite one of them. It stays unverified until an NPI-verified clinician or a Synapse admin approves it. Approving records that person's name.
Most-cited researchers publishing on Cardio-oncology.