
Heart Failure
Heart transplant outcomes, rejection, and donor management
Synthesized from 34 evidence-backed clinical questions linked to this topic — 1 supporting the intervention, 1 against the intervention, 1 still contested.
Does simvastatin vs placebo improve outcomes in cardiac allograft vasculopathy?
Low Certainty− Favors harmsimvastatin vs placebo
7 studies (431 patients) provide low-certainty evidence against benefit of simvastatin for the outcome in cardiac allograft vasculopathy.
Does ivabradine vs beta-blockers improve outcomes in Heart Transplantation?
Low Certainty+ Favors benefitivabradine vs beta-blockers
2 studies (224 patients) provide low-certainty evidence for benefit of ivabradine for the outcome in Heart Transplantation.
Emerging evidence with 15 primary claims
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Mortality Among Referral Patients With Hypertrophic Cardiomyopathy vs the General European Population
JAMA Cardiology — Lorenzini M — Nov 2019
Relationship between myocardial collagen and echo amplitude in non-fibrotic hearts
European Heart Journal — Lythall D — Mar 1993
Addressing complications of large bore access in endovascular and cardiovascular procedures: An illustration of treatment options
Vascular — Mukherjee D — Dec 2024
Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease
Cardiovascular Research — Azzawi M — Sep 1999
Advanced Heart Failure With Preserved Systolic Function in Nonobstructive Hypertrophic Cardiomyopathy
Circulation Heart Failure — Rowin E — Sep 2014
Rapid onset of fulminant myocarditis portends a favourable prognosis and the ability to bridge mechanical circulatory support to recovery
European Journal of Cardio-Thoracic Surgery — Atluri P — May 2012
Myocardial high-energy phosphate metabolism and allograft rejection in patients with heart transplants.
Radiology — Bottomley P — Oct 1991
Cardiovascular magnetic resonance techniques and findings in children with myocarditis: a multicenter retrospective study
Journal of Cardiovascular Magnetic Resonance — Banka P — Jan 2015
Predictive value of E/A and E/E′ Doppler indexes for cardiac events in heart transplant recipients
Clinical Transplantation — Ambrosi P — May 2016
Intermediate term results of total lymphoid irradiation for the treatment of non-specific graft dysfunction after heart transplantation
European Journal of Cardio-Thoracic Surgery — Madden B — May 1999
Incidence and clinical relevance of coronary calcification detected by electron beam computed tomography in heart transplant recipients
European Heart Journal — Ludman P — Feb 1999
Péripartum cardiomyopathy: Causes, diagnosis, and treatment
Cleveland Clinic Journal of Medicine — Ramaraj R — May 2009
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Heart transplantation (also known as cardiac transplant, heart transplant, HTx). Heart transplant outcomes, rejection, and donor management
As of 2026-08-14, the scientific consensus on Heart transplantation is emerging. Emerging evidence with 15 primary claims Based on 15 analyzed claims across Synapse's enriched corpus, the evidence shows.
This evidence brief synthesizes Synapse's enriched cardiology corpus; cite as synapsesocial.com/topics/heart-transplantation.
Deterministic synthesis from Synapse's enriched corpus — 57 words. No AI-generated novel content; every figure is sourced from the underlying paper, guideline, or trial record linked on this page.
Explore every Heart transplantation paper on Synapse with AI-enriched clinical evidence, PICO analysis, and methodology classification.
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