Visceral adipose tissue (VAT) area was significantly associated with major morphological and functional echocardiographic alterations in normotensive obese patients (p < 0.0001).
Cross-Sectional (n=46)
p-value: p=<0.0001
OBJECTIVE: To evaluate the relationship of echocardiographic characteristics and visceral adipose tissue (VAT) distribution in normotensive obese patients. RESEARCH METHODS AND PROCEDURES: Echocardiographic parameters were assessed in 28 normotensive obese patients 7 men, 21 women, mean age, 43.2 years; mean body mass index (BMI), 37.2 kg/m(2); 10 with impaired glucose tolerance (IGT); 6 with type 2 diabetes and 18 sex- and age-matched healthy, normal-weight controls (4 men, 14 women; mean age, 45.8 years; mean BMI, 22.4 kg/m(2)) by an M-mode, color-doppler videofluoroscope. VAT in the obese patients was assessed by computed tomography (at L4 level). RESULTS: The obese patients had a significantly larger internal diastolic left ventricular (LV) diameter (p 130 cm(2) than with <130 cm(2). In the multivariate regression analysis, only VAT (p < 0.0001), waist-to-hip ratio (p < 0.001), and sex (p < 0.001) were associated with the most important echocardiographic alterations. DISCUSSION: The morphological and functional echocardiographic alterations usually found in normotensive obese patients closely correlate with the amount of intra-abdominal fat deposition, even in the presence of diabetes or IGT.
Morricone et al. (Sat,) conducted a cross-sectional in Normotensive obesity (n=46). Visceral adipose tissue (VAT) distribution vs. Normal-weight controls and VAT area <130 cm2 was evaluated on Relationship of echocardiographic characteristics and visceral adipose tissue (VAT) distribution (p=<0.0001). Visceral adipose tissue (VAT) area was significantly associated with major morphological and functional echocardiographic alterations in normotensive obese patients (p < 0.0001).