Smoking cessation in perimenopausal to postmenopausal women was associated with greater weight gain but modestly associated with positive changes in cardiovascular risk factors.
Cohort
Does smoking cessation affect weight gain and cardiovascular risk factors in women transitioning from premenopause to postmenopause?
Smoking cessation during the menopausal transition is associated with greater weight gain but does not worsen cardiovascular risk factors, and may modestly improve HDL cholesterol.
OBJECTIVES: The relationship between smoking cessation, subsequent weight gain, and cardiovascular disease risk factors from premenopause to postmenopause was studied. METHODS: Healthy Women Study participants were assessed for changes in coronary heart disease risk factors from a premenopausal baseline assessment to first- and second-year postmenopausal assessments. RESULTS: Although ex-smokers gained substantially more weight than nonsmokers and smokers, they did not experience a greater increase in cardiovascular risk factors. In fact, the results indicated a trend toward ex-smokers' high-density lipoprotein cholesterol levels increasing slightly more than those of nonsmokers and smokers. CONCLUSIONS: Smoking cessation in perimenopausal to postmenopausal women is associated with greater weight gain but appears to be modestly associated with certain positive changes in cardiovascular risk factors.
Burnette et al. (Thu,) conducted a cohort in Cardiovascular risk factors during menopause. Smoking cessation vs. Nonsmokers and smokers was evaluated on Changes in coronary heart disease risk factors and weight gain. Smoking cessation in perimenopausal to postmenopausal women was associated with greater weight gain but modestly associated with positive changes in cardiovascular risk factors.