Calculation of the impulse response function of the arterial system in dogs revealed that the height of the exponential decay relates to total arterial compliance and peaks indicate reflection sites.
Arterial system hemodynamics
Balloon occlusion of the descending aorta vs Control dog
Impulse response function and total arterial compliance
The impulse response function and the input impedance of the systemic arterial tree emphasize different aspects of this system. The impulse response function is calculated via inverse Fourier transformation of the input impedance. The effects of truncation of the impedance are reduced by subjecting the data to a Dolph-Chebyshev filter. The impulse response functions of a windkessel model, a uniform tube model, and of the arterial system of the dog, are given. The impulse response functions of the windkessel model and of the arterial system of the control dog show a sharp initial peak followed by an exponential decay (equal decay time as that of the diastolic pressure tracing). The height of the decay extrapolated to time zero is related to total arterial compliance. Total arterial compliance calculated in this way agrees with the value calculated from the ratio of the time constant of the diastolic pressure decay and peripheral resistance. The presence of peaks in the impulse response function indicates a distinct reflection site as shown in the uniform tube model and found in the dog with balloon occlusion of the descending aorta. The measurement of the time intervals between these peaks and the start of excitation together with the pulse wave velocity enable us to calculate the distance between the location of the reflecting site and the heart.
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Swamy Laxminarayan
Idaho State University
Pieter Sipkema
Amsterdam UMC Location Vrije Universiteit Amsterdam
Nicolaas Westerhof
Brooke Army Medical Center
IEEE Transactions on Biomedical Engineering
University of Amsterdam
Brain Physiology Lab
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Laxminarayan et al. (Wed,) conducted a other in Arterial system hemodynamics. Balloon occlusion of the descending aorta vs. Control dog was evaluated on Impulse response function and total arterial compliance. Calculation of the impulse response function of the arterial system in dogs revealed that the height of the exponential decay relates to total arterial compliance and peaks indicate reflection sites.
synapsesocial.com/papers/6a2022c3f8c30f43cdfbee45 — DOI: https://doi.org/10.1109/tbme.1978.326244