May 29, 2014Open Access
View Full PaperTertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
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Abstract
T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures in the shaping of an efficient and beneficial immune response in lung cancer patients.