A family history of Type 2 diabetes mellitus does not impair resting heart rate variability when adjusted for metabolic and anthropometric characteristics (P > 0.05).
Cross-Sectional (n=91)
No
Does a family history of Type 2 diabetes mellitus impair resting heart rate variability in subjects without metabolic disorders?
A family history of Type 2 diabetes mellitus does not independently impair resting heart rate variability when accounting for metabolic factors like cholesterol and triglycerides.
p-value: p=> 0.05
AIMS: To investigate the influence of a family history of Type 2 diabetes mellitus (T2DM) on resting heart rate variability in the absence of concomitant metabolic disorders. METHODS: We studied 55 first-degree relatives (FDRs) of subjects with T2DM and 36 control subjects without any known family history of diabetes. FDRs were recruited from a University Hospital out-patient diabetes clinic. The protocol included: oral glucose tolerance test (30, 60, 90 and 120 min after ingestion of 75 g glucose) blood glucose, plasma insulin, cholesterol and subfractions, triglycerides, leptin and C-reactive protein. Heart rate variability (HRV) at rest was determined by spectral analysis of interbeat intervals recorded during 10 min in the supine position. RESULTS: HRV was lower in FDRs compared with control subjects (P 0.05). CONCLUSIONS: A family history of T2DM, in the absence of concomitant metabolic disorders, does not impair heart rate variability.
Neves et al. (Wed,) conducted a cross-sectional in Family history of Type 2 diabetes mellitus (n=91). Family history of Type 2 diabetes mellitus vs. No known family history of diabetes was evaluated on Heart rate variability (HRV) at rest (p=> 0.05). A family history of Type 2 diabetes mellitus does not impair resting heart rate variability when adjusted for metabolic and anthropometric characteristics (P > 0.05).