Key points are not available for this paper at this time.
With a view to the possible use of transposable elements (TEs) as a mechanism to drive genes into insect vector populations, we used a three-parameter density dependent growth equation to examine the critical parameter values that determine whether or not a mobile element will spread and become fixed in a finite diploid vector population. Populations were simulated with parameter values affecting size, reproductive rate, density-dependence, and transposition efficiency of the mobile element. Simulations indicated that an equilibrium was reached quickly, typically in 0.75 that reduces fertility < 25% will become fixed when introduced at a frequency as low as 1% of the total population. These results are consistent with previously reported population genetics models. They suggest that engineered transposons with a wide range of properties may be used to drive genes, such as those for parasite resistance, into wild vector populations.
Ribeiro et al. (Sat,) studied this question.