Central obesity may contribute to pseudotumor cerebri by increasing intra-abdominal and cardiac filling pressures, which impede cerebral venous return.
These data support the hypothesis that central obesity raises intra-abdominal pressure, which increases pleural pressure and cardiac filling pressure, which impede venous return from the brain, leading to increased intracranial venous pressure and increased intracranial pressure associated with pseudotumor cerebri.
Sugerman et al. (Fri,) studied this question.