ICD implantation in patients aged ≥80 years was associated with similar 1-year survival compared to patients aged 70-79 years (93% vs 91%, P>0.05).
Cohort (n=212)
No
Does Implantable Cardioverter Defibrillator (ICD) implantation provide similar survival and safety in patients ≥80 years compared to patients 70-79 years?
ICD implantation in octogenarians appears safe and feasible, with 1-year survival and complication rates comparable to patients aged 70-79 years.
Absolute Event Rate: 93% vs 91%
p-value: p=> 0.05
This article addresses the feasibility and safety of ICD therapy in patients >80 years of age. Recent trials have expanded the indication for ICD implantation to include an increasing number and variety of patients. The feasibility of ICD implantation in elderly patients has not been adequately studied. A prospectively collected single center ICD database was analyzed to assess the safety and feasibility of ICD implantation in elderly patients. Patients were divided based on age into two groups (group 1: 70-79 years of age, n = 183; group 2: >or=80 years of age, n = 29). The two groups were similar in gender distribution, NYHA class, and indication for implantation. The actuarial survival was not significantly different between groups 1 and 2 (P > 0.05; primary endpoint), with a 1-year survival of 91% and 93% in groups 1 and 2, respectively, (P = NS). The complication rates at the time of ICD implantation were similar in groups 1 and 2 (6.6% and 13.1%, respectively, P = 0.16). Age alone may not be sufficient criteria to exclude ICD implantation. The current consensus guidelines for ICD implantation appear to be generalizable to treating octogenarians who are otherwise medically fit.
Noseworthy et al. (Mon,) conducted a cohort in Indications for Implantable Cardioverter Defibrillator (ICD) (n=212). Age ≥80 years (ICD implantation) vs. Age 70-79 years (ICD implantation) was evaluated on Actuarial survival (p=> 0.05). ICD implantation in patients aged ≥80 years was associated with similar 1-year survival compared to patients aged 70-79 years (93% vs 91%, P>0.05).