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The use of the NSD concept in practical radiotherapy is simplified by the introduction of time, dose, and fractionation (TDF) factors, which are proportional to partial tolerances, but are not dependent upon any specific NSD value. Detailed examples are given of the utilization of TDF factor tables, which are simple to use, general in application, and which help to ensure the correct interpretation of the basic NSD concepts. Computers, slide-rules, or even log tables, are not requires.
Orton et al. (Sun,) studied this question.