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Based on our data, KRAS mutations are not rare among never smokers with lung adenocarcinoma and such patients have a distinct KRAS mutation profile. The etiologic and biological heterogeneity of KRAS mutant lung adenocarcinomas is worthy of further study.
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Gregory J. Riely
Mark G. Kris
Daniel G. Rosenbaum
Clinical Cancer Research
Memorial Sloan Kettering Cancer Center
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Riely et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69de6ce4bf539e22705588db — DOI: https://doi.org/10.1158/1078-0432.ccr-08-0646
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