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Biological Activity of a Growth Factor for Ovarian Cells | Synapse

September 1, 1974Proceedings of the National Academy of Sciences13 citationsOpen Access

Biological Activity of a Growth Factor for Ovarian Cells

KJKenneth L. Jones DGDenis Gospodarowicz

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Abstract

The biological activity of a protein growth factor is described. This factor was isolated from bovine pituitary tissue, and its activity was tested on cells of rat ovarian origin. Activity was assayed as growth-promoting potential measured by cell counts and is concentrationdependent. Similar growth stimulation was not produced by several cyclic nucleotides tested, neither was there crossreactivity between this growth factor and a chemically similar one produced by rat liver cells.

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Cite This Study

Jones et al. (1974) studied this question.

synapsesocial.com/papers/6a63f7a4ccedfd04c9928bb8 https://doi.org/https://doi.org/10.1073/pnas.71.9.3372

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3Amino Acid Sequence of a Biologically Active Fragment of Bovine Growth Hormone1972 · 34 citations
4The Presence of a Common Type of Subunit in Bovine Thyroid-stimulating and Luteinizing Hormones1970 · 155 citations
5Growth Control in Cell Cultures.1972 · 126 citations